Use of fibrinolytic agents in the management of complicated parapneumonic effusions and empyemas

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Use of fibrinolytic agents in the management of complicated parapneumonic effusions and empyemas.

BACKGROUND Standard treatment for pleural infection includes catheter drainage and antibiotics. Tube drainage often fails if the fluid is loculated by fibrinous adhesions when surgical drainage is needed. Streptokinase may aid the process of pleural drainage, but there have been no controlled trials to assess its efficacy. METHODS Twenty four patients with infected community acquired parapneu...

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Fibrinolytics in parapneumonic effusions/empyemas.

We read with interest the point/counterpoint debate by Drs Corcoran, Rahman, Colice, and Idell in CHEST (January 2014) 1 4 regarding thrombolytics in parapneumonic eff usions (PPEs)/empyemas. We have treated . 400 patients with PPEs and empyemas with intrapleural tissue plasminogen activator (tPA), and only four patients with chronic empyema needed decortication. We published two articles; one ...

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Intrapleural fibrinolytic agents for empyema and complicated parapneumonic effusions: a meta-analysis.

BACKGROUND Randomized controlled trials have shown conflicting findings about the role of intrapleural fibrinolytic therapy for the treatment of empyema and complicated parapneumonic effusions in adult patients. OBJECTIVES To assess the clinical efficacy and summarize the current evidence of intrapleural fibrinolytic use in patients with empyema and complicated parapneumonic effusions in adul...

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Intrapleural therapy in management of complicated parapneumonic effusions and empyema

Empyema thoracis causes high mortality, and its incidence is increasing in both children and adults. Parapneumonic effusions (PPEs) develop in about one-half of patients hospitalized with pneumonia, and their presence increases mortality by about four-fold. PPEs can be divided into simple PPEs, complicated PPEs, and frank empyema. Two guideline statements on the management of PPEs in adults hav...

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Thoracoscopic Management of Complicated Parapneumonic Effusions in Young Children

Method: Eleven patients under the age of two year with the diagnosis of complicated parapneumonic effusions underwent thoracoscopic management. The patients had chest X-ray, Ultrasound and CT scan of the chest. The patients received antibiotic 3-6 weeks prior to thoracoscopy without improvement. The patients received fibrinolytic agent on the second postoperative day. Three trocars used, one 5 ...

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ژورنال

عنوان ژورنال: Thorax

سال: 1998

ISSN: 0040-6376

DOI: 10.1136/thx.53.2008.s65